Contact an Account ManagerAnalytical studies on b-lactam antibiotics III. Automated HPLC method for the determination of the orally active antibiotic ceftibuten in human plasma and urine
Summary
Type: HPLC
Application #: 103490
Catalog#: 720120.46 - MN HPLC Column, Nucleosil C18, 100A, 5um, 4.6x150mm
Detection: UV, 256nm
Conditions: eluent: 5mM tetra-n-butylammonium bromide, 5mM tetra-n-amylammonium bromide, 8mM monobasic ammonium phosphate, pH 5.0 - acetonitrile - methanol (65:25:10, v/v)
flow rate programme with column switching
Authors: Matsuura A
Source: J Chromatogr 494 (1989) 231 - 245
Details
Legend: Fig. 1. Chromatograms of A) human urine from a healthy subject (control), B) human urine from the same subject collected 2 - 4h after oral administration of 200mg of compound I (I, 94.6µg/ml; II, 5.5µ